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KMID : 0614620210780060349
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Korean Journal of Gastroenterology
2021 Volume.78 No. 6 p.349 ~ p.352
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Natural Killer-cell Enteropathy of the Stomach in an Elderly Woman: A Case Report
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Koo Ye-Young
Lee Jin
Kim Bo-Mi
Jeong Su-Jin
Oh Eun-Hye
Park Yong-Eun
Park Jong-Ha
Kim Tae-Oh
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Abstract
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Natural killer (NK) cell enteropathy is not well understood. Although NK-cell enteropathy is typically benign, aggressive NK-cell lymphoma is an important differential diagnosis. This paper reports a rare case of NK-cell enteropathy of the stomach presenting with dyspepsia and weight loss. In this case, upper endoscopy revealed an ulcer-like lesion (approximately 7 mm) surrounded by erythema, edema, and mucosal hemorrhage. The biopsy revealed atypical lymphocyte cells expressing CD56 without an Epstein-Barr virus infection, which is consistent with NK-cell enteropathy. Follow-up endoscopy 2 months later revealed lesion regression with mild erythema. The patient was observed closely for 6 months, with no evidence of lymphoma.
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KEYWORD
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Killer cells, natural, Intestinal diseases, Lymphoma, Stomach
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